non alcoholic fatty liver. Other inflammatory liver diseases
Conditions
Sponsors
Gonabad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Presence of fat accumulation in liver ultrasound evaluation and grade 2 fatty liver and increased liver enzymes (ALT and AST) above 40 The age of the people should be between 20-60 years. Body mass index above 25 kg/m2 Ability to read and write
Exclusion criteria
Exclusion criteria: Having chronic lung diseases, other liver diseases, heart conditions, and any chronic kidney or digestive disease History of drinking alcoholic beverages Smoking and drug use Use of diuretics and nonsteroidal anti-inflammatory drugs (NSAIDs), estrogen, tamoxifen, corticosteroids, and blood sugar-lowering drugs within 3 weeks before the start of the study and during the study Evidence of viral hepatitis infection pregnancy and lactation follow of special diet Regular consumption of antioxidant supplements such as vitamins E, C, and silymarin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expression of long non-coding RNA MEG3. Timepoint: Initially and 12 weeks (84 days) after starting sumac supplementation. Method of measurement: Real -Time PCR.;Expression of long non-coding RNA SRA. Timepoint: Initially and 12 weeks (84 days) after starting sumac supplementation. Method of measurement: Real -Time PCR. | — |
Secondary
| Measure | Time frame |
|---|---|
| Anthropometric indices (weight, body mass index, and waist circumference). Timepoint: Initially and 12 weeks (84 days) after starting sumac supplementation. Method of measurement: Scale and Wall-mounted height gauge. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Rashidmayvan
Gonabad University of Medical Sciences
Outcome results
None listed