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The effect of magnesium sulfate on the heart and respiration of multiple trauma patients under mechanical ventilation

The effect of magnesium sulfate on hemodynamic and respiratory parameters of multiple trauma patients under mechanical ventilation

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230719058853N1
Enrollment
104
Registered
2023-08-12
Start date
2023-08-23
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple trauma. Unspecified multiple injuries

Interventions

Intervention 1: Intervention group: 2 g magnesium sulfate 20% (Shahid Ghazi Co., Tabriz, Iran) in daily serum within 24 hours. Intervention 2: Control group: Only daily serum within the first 24 hours

Sponsors

Vice-Chancellery for Research Hormozgan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Multiple trauma Mechanical ventilation Admission to the intensive care unit within 24 hours of trauma Age 18-70 years

Exclusion criteria

Exclusion criteria: History of pulmonary diseases such as asthma and chronic obstructive pulmonary disease Pulmonary contusion Pneumothorax Cardiovascular instability

Design outcomes

Primary

MeasureTime frame
Blood pressure. Timepoint: Every 6 hours within the first 24 hours. Method of measurement: The monitoring device of the intensive care unit.;Oxygen saturation. Timepoint: Every 6 hours within the first 24 hours. Method of measurement: Pulse oximeter.

Secondary

MeasureTime frame
Heart rate. Timepoint: Every 6 hours within the first 24 hours. Method of measurement: The monitoring device of the intensive care unit.;Pulmonary compliance. Timepoint: Every 6 hours within the first 24 hours. Method of measurement: The ventilator device.;Airway resistance. Timepoint: Every 6 hours within the first 24 hours. Method of measurement: The ventilator device.;Arterial blood gas. Timepoint: Every 12 hours within the first 24 hours. Method of measurement: Arterial blood gas measurement in arterial blood sample.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSarina Charani

Bandare-abbas University of Medical Sciences

sarinach9678@yahoo.com+98 76 3334 7000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026