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Comparison of magnesium sulfate and lidocaine spray on hemodynamic changes due to laryngoscopy

Comparison of the effect of magnesium sulfate and lidocaine spray on hemodynamic changes due to laryngoscopy and Tracheal intubation - Clinical trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230719058846N1
Enrollment
100
Registered
2023-10-31
Start date
2023-11-21
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodynamic changes including heart rate and blood pressure and ECG changes after laryngoscopy. Other intraoperative and postprocedural complications and disorders of the circulatory system, not elsewhere classified

Interventions

Intervention 1: Intervention group: In one of the studied patients, 5 puffs of lidocaine 10% containing 10 mg of lidocaine is sprayed in the throat. In the next step for both groups of atracurium rela

Sponsors

Karaj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: All patients aged 18 to 40 years old who are in ASA (American Society Anesthesiology) Class I,II. BMI is in the range of 19 to 25 Have a mallampaty score of one or two

Exclusion criteria

Exclusion criteria: 1. Patient dissatisfaction or withdrawal from participation in the study 2. Having sensitivity to magnesium sulfate and lidocaine 3. Being a smoker 4. Having a cold, cough and sputum 5.Have a mallampaty score of three or four 6. In terms of airway examination in the Lemon Law criteria have problem of intubation and diffusion should have. 7.If the laryngoscopy lasts longer than 15 seconds. If there is a problem during laryngoscopy and the patient has a difficult intubation. 8. Having a history of arterial hypertension, tachycardia, bradycardia and arrhythmia 9. Use of hemodynamic drugs such as indral and ...

Design outcomes

Primary

MeasureTime frame
Systolic and diastolic blood pressure. Timepoint: Minutes 1, 3, 5, 7 and 10 from the start of the intervention. Method of measurement: Operating Room Pressure Gauge.;Heart rate. Timepoint: Minutes 1, 3, 5, 7 and 10 from the start of the intervention. Method of measurement: Heart Rate Indicator Device in Operating Room.

Secondary

MeasureTime frame
Changes in ECG. Timepoint: Minutes 1, 3, 5, 7 and 10 from the start of the intervention. Method of measurement: Electrocardiogram Monitor.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Banafsheh Mashak

Karaj University of Medical Sciences

mashakbanafsheh@yahoo.com+98 26 3222 2021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 6, 2026