Female infertility. Female infertility of uterine origin
Conditions
Interventions
Intervention 1: Intervention group: LactoVag vaginal suppository (Lactobacillus rhamnosus10^9 CFU, Zist Takhmir Company, Tehran, Iran) two weeks before embryo transfer. Intervention 2: Control group:
Sponsors
Hamedan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Age less than 40 years Maximum FSH level of 15 IU/ml Absence of any systemic diseases (hypertension, diabetes, antiphospholipid syndrome, lupus, thrombophilia and thyroid diseases) Normal uterine cavity with sufficient endometrial thickness of 7 mm Absence of hydrosalpinx
Exclusion criteria
Exclusion criteria: Diagnosis of Asherman's syndrome Diagnosis of polyps and fibroids by hysteroscopy Refusal to participate in the study Presence of chronic disease The presence of vaginal infectious discharge Receiving medical treatment chronically Repeated IVF failure (more than 3 times in previous cycles) Presence of clinical symptoms of vaginal infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chemical pregnancy rate. Timepoint: Two weeks after embryo transfer. Method of measurement: Serum level of ß-HCG. | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical pregnancy rate. Timepoint: 4-6 weeks after embryo transfer. Method of measurement: Transvaginal ultrasound. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Ehsan Mousavi
Tabriz University of Medical Sciences
Outcome results
None listed