Spinal Diseases. Disease of spinal cord, unspecified
Conditions
Interventions
Intervention 1: Intervention group: Intrathecal morphine (0.2 mg) which is injected in the L3-L4 or L4-L5 intervertebral space in a single dose at the end of the surgery in the prone position using a
Sponsors
Kerman University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: Age between 18 to 85 American Society of Anesthesia (ASA) classification I or II Candidates for surgeries of spine Informed consent to enter the study
Exclusion criteria
Exclusion criteria: Pregnancy or breastfeeding at the time of enrollment History of allergy to local anesthetic agents History of cardiac or renal failure Opioid use disorder Uncontrolled blood pressure Body mass index above 40 kg/m2 Preoperative heart rate less than 50 beats/min Spinal cord injuries that could interfere with the pain assessment Incidental intraoperative durotomy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain intensity. Timepoint: 4, 6, 12, 18 hours post-operation. Method of measurement: Visual Analogue Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Time interval from the surgical procedure until the patient required supplementary analgesics. Timepoint: From the operation till maximum 18 hours. Method of measurement: Timer.;Side effects (Postoperative nausea/vomiting, pruritus, dyspnea, respiratory depression). Timepoint: From the operation till maximum 18 hours. Method of measurement: Subjective assessment. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Ehsan Parsa
Kerman University of Medical Sciences
Outcome results
None listed