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Comparing the effects of three therapeutic regimens prednisolone on platelet increase in patients with primary immune thrombocytopenic purpura

Comparing the effects of three therapeutic regimens of oral prednisolone, intravenous methylprednisolone, and oral prednisolone plus recombinant human thrombopoietin on platelet increase in patients with primary immune thrombocytopenic purpura: a clinical trial study.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230717058813N1
Enrollment
75
Registered
2023-09-22
Start date
2023-10-23
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

primary immune thrombocytopenia purpura. Other coagulation defects

Interventions

Intervention 1: The first group: they will receive pulse methylprednisolone 2-3 mg/kg intravenously for 3 days every 2 weeks for 4 weeks until re-examination. Intervention 2: Control group: They will

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: age of 18-60 years, having a normal spleen size suffering from Immune thrombocytopenia (ITP)

Exclusion criteria

Exclusion criteria: history of chronic kidney diseases history of diabetes pregnant women or pregnancy during study history of secondary Immune thrombocytopenia (ITP) such as (Antiphospholipid syndrome, Myelodysplastic syndromes and vasculitis) patients under treatment with any drugs within 3-month before participating in study

Design outcomes

Primary

MeasureTime frame
Platelet value in cell blood count test. Timepoint: Monthly. Method of measurement: Cell blood count test.

Secondary

MeasureTime frame
Side effect of treatment with corticosteroids. Timepoint: Six-months after treatment. Method of measurement: Clinical visit.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReyhaneh Azimi Noubari

Shahid Beheshti University of Medical Sciences

reyhaneh.azimi92@gmail.com+98 21 7343 3000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026