Skip to content

Investigation and effect of intravenous injection of dexamethasone and magnesium sulfate on pain

Study the Effect of Intravenous of Dexamethasone versus Magnesium Sulphate on postoperative pain after laparoscopic Cholecystectomy surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230717058811N1
Enrollment
60
Registered
2023-10-16
Start date
2023-06-20
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain after head cystectomy surgery. Retained cholelithiasis following cholecystectomy

Interventions

Intervention 1: Intervention group: Patients in group M will be given a bolus dose of 50 mg/kg magnesium sulfate in 15 minutes and an infusion of 10 mg/kg magnesium sulfate in normal saline until the

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients between 18-70 years old Candidate for elective laparoscopic cere cystectomy surgery Action satisfaction

Exclusion criteria

Exclusion criteria: known allergy to one of the study drugs (dexamethasone/magnesium sulfate) Liver-kidney-heart dysfunction History of taking steroid drugs before surgery Neuromuscular disease Opioid or analgesic use within 3 days before the study Taking calcium channel blockers Failure to sign written consent

Design outcomes

Primary

MeasureTime frame
Visual Analogue Scale (VAS). Timepoint: Based on the VAS criteria at certain times (immediately after induction, one hour, two hours and 24 hours after the operation). Method of measurement: After the surgery, the patient will be monitored for 2 hours in recovery and the pain intensity of the patients will be measured and recorded every half hour by a person who is not aware of the groups.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactTirazheh Hazrati Yadkoori

Ahvaz University of Medical Sciences

hazrati.t@ajums.ac.ir+98 912 890 7911

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026