Bleeding during Septorhinoplasty surgery. Other antihypertensive drugs, not elsewhere classified
Conditions
Interventions
Intervention 1: Intervention group: Diazepam 0.1 mg per kilogram orally and Clonidine 3 micrograms per kilogram orally 90 minutes before surgery are prescribed by the anesthesiologist in a room with a
Sponsors
Qazvin University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: Candidate for Septorhinoplasty Age range 20-45 Physical class above 2 Willingness to participate in research with informed consent after giving necessary and sufficient explanations about the study
Exclusion criteria
Exclusion criteria: Having any lung disease History of Rhinoplasty surgery History of smoking, alcohol and drugs Chronic mental and physical illness (Schizophrenia, Diabetes, etc.) Vision and hearing problems and other disabilities Long-term use of Corticosteroids, antihistamines, narcotics and painkillers Having diabetes Coagulation disorders Ischemic heart disease History of taking beta blockers or calcium channel blockers patients with systolic blood pressure less than 100 mmHg or heart rate less than 40per minute patients with relative or absolute prohibition of general anesthesia Pregnancy, breast feeding and abortions less than 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The effect of Clonidine on blood pressure during Septorhinoplasty. Timepoint: Systolic and diastolic blood pressure are measured before induction of anesthesia, after intubation of the patient, at the end of surgery and after transfer to recovery. Method of measurement: Blood pressure measurement is done by monitoring device and recorded by evaluator.;The effect of clonidine on the amount of bleeding during Septorhinoplasty. Timepoint: After surgery. Method of measurement: The amount of blood in the suction device and the number of completely blood gases. Before the operation, a strong pharyngeal peg is inserted by the surgeon, and at the end of the operation, after the peg is removed, the blood in the nasopharynx is suctioned and added to the amount of bleeding. | — |
Secondary
| Measure | Time frame |
|---|---|
| Effect of Clonidine on heart rate. Timepoint: Before induction of anesthesia, after patient intubation, at the end of surgery and after transfer to recovery. Method of measurement: Monitoring device.;Breathing rhythm. Timepoint: Before induction of anesthesia, after patient intubation, at the end of surgery and after transfer to recovery. Method of measurement: Monitoring device. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMostafa Ghasemi
Qazvin University of Medical Sciences
Outcome results
None listed