The participants are healthy and trained male mountaineer..
Conditions
Interventions
Intervention 1: Ginkgo biloba group: Apart from the familiarization sessions and initial measurements, the subjects attend the laboratory twice and perform the Stroop test and reaction time in normal
Sponsors
Razi University
Eligibility
Sex/Gender
Male
Age
18 Years to 44 Years
Inclusion criteria
Inclusion criteria: Active mountaineer men aged 18 to 44 years (history of climbing to altitudes higher than 4000 meters and regular climbing activity in the past one year) History of AMS in previous nights at altitudes higher than 3000 meters Body mass index between 18.5 and 24.9 Having general health to participate in sports activities approved by the doctor Regular aerobic exercise in 6 months before the beginning of the research (at least three sessions per week, including hiking)
Exclusion criteria
Exclusion criteria: Suffering from any chronic disease History of cognitive disorders or neurological diseases History of allergies and sensitivities Use of any sports supplements in the two months before the start of the study Smoking and alcohol consumption Donating blood in the 2 months before the start of the study History of staying at higher altitudes From 2000 meters in two months before the beginning of the research, sleeping at an altitude above 2700 meters in two weeks before the beginning of the research Taking acetazolamide drug in two weeks before the beginning of the research Allergy to acetazolamide and sulfonamides Suffering from color blindness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in the time to reach exhaustion in a submaximal endurance exercise under hypoxic conditions. Timepoint: After administration of ginkgo biloba or placebo under hypoxic conditions. Method of measurement: Record time using a stopwatch.;Selective visual reaction time. Timepoint: At the beginning of the study to evaluate the level of cognitive function, after taking ginkgo biloba or placebo and before and after applying hypoxia. Method of measurement: Cognitive performance is assessed using a reaction time device. (RESPONSE PANEL 63035A, LAFAYETTE, INDIANA).;Cognitive function. Timepoint: At the beginning of the study to evaluate the level of cognitive function, after taking ginkgo biloba or placebo and before and after applying hypoxia. Method of measurement: Using the color-word Stroop test.;Sense of pleasure. Timepoint: Before and after reaching exhaustion in a submaximal endurance exercise under normobaric hypoxia conditions. Method of measurement: Using an 11-item emotion scale.;Arousal level. Timepoint: Before and after reaching exhaustion in a submaximal endurance exercise under normobaric hypoxia conditions. Method of measurement: Using a 6-item scale of perceived arousal.;The degree of perception of pressure. Timepoint: Before and after reaching exhaustion in a submaximal endurance exercise under normobaric hypoxia conditions. Method of measurement: Using a pressure perception scale of 6 to 20 borg. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactVahid Tadibi
Razi University
Outcome results
None listed