chronic stroke. Cerebral infarction, unspecified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: stroke-induced hemiplegia A minimum of six months have passed since the occurrence of the stroke, indicating a chronic stage of the disease. The degree of spasticity exhibited by the elbow flexor muscles on the affected side, as determined by the Modified Modified Ashworth Scale (MMAS), is a minimum of 1. Age 30-75 Ability to follow instructions
Exclusion criteria
Exclusion criteria: Individuals undergoing other treatments to alleviate spasticity The administration of pharmacological interventions aimed at reducing spasticity Not having any contraindications to using the TMS device, such as a history of seizures, epilepsy (the person themselves or a first-degree family member), a history of head injury or brain injury, metal in the head (outside the mouth) such as surgical clips, cochlear implants, or welded parts, a history of negative reactions to MRI or TMS, a history of brain-related diseases such as MS or brain tumors, a history of fainting, or a history of severe headaches,pregnancy or conception intention within the last three months, Past use of drugs known to reduce the seizure threshold, such as imipramine, amitriptyline, doxepin, nortriptyline, maprotiline, chlorpromazine, clozapine, foscarnet, ganciclovir, ritonavir, theophylline, phenytidine, ketamine, gamma hydroxybutyrate, amphetamine, cocaine, and recent use of drugs or alcohol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Corticospinal excitability. Timepoint: prior to the commencement of the intervention, after three sessions of the intervention, and one week subsequent to the intervention. Method of measurement: The transcranial magnetic stimulation device is utilized to measure the resting motor threshold in elbow flexor muscles while simultaneously recording the corresponding motor-evoked potential via electromyography.;Spasticity of the elbow flexor muscles. Timepoint: prior to the commencement of the intervention, after three sessions of the intervention, and one week subsequent to the intervention. Method of measurement: Modified Modified Ashworth Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| The active and passive range of motion of the elbow joint. Timepoint: prior to the commencement of the intervention, after three sessions of the intervention, and one week subsequent to the intervention. Method of measurement: The assessment will be conducted utilizing a goniometry.;Passive resistance force. Timepoint: prior to the commencement of the intervention, after three sessions of the intervention, and one week subsequent to the intervention. Method of measurement: the hand-held dynamometer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Tehran University of Medical Sciences