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Investigating the effect of chicory in the treatment of thalassemia

Evaluation the effect of Chicory in decreasing serum Ferritin and liver enzymes in major Thalassemia patients

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230704058674N1
Enrollment
52
Registered
2023-12-21
Start date
2024-01-21
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Beta Thalassemia major. Beta thalassemia

Interventions

Intervention 1: Intervention group: Chicory herbal extract prepared from Tehran School of Traditional Medicine with a concentration of 417 mg per cc, 5 cc every 12 hours for 3 months. Intervention 2:

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Consent of patients to participate in the study thalassemia major patients treated with periodic pack cell transfusion ferritin>500

Exclusion criteria

Exclusion criteria: disinclination to participate or continue studying Occurrence of skin complications or other symptoms suggestive of sensitivity to chicory plant extract Viral hepatitis or known liver disease

Design outcomes

Primary

MeasureTime frame
Ferritin. Timepoint: Initial ferritin measurement (before the start of the intervention), 3 months after consumption of chicory. Method of measurement: Biochemistry blood test.

Secondary

MeasureTime frame
Liver enzyme. Timepoint: Liver enzyme measurement at the beginning of the study (before consuming chicory) and three months after consuming chicory. Method of measurement: Biochemistry blood test.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactmozhgan jafari

Arak University of Medical Sciences

mozhgaanjafari1994@gmail.com+98 86 3403 5290

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026