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Evaluating diagnostic value of 99mTc-CXCR4 scan in glioblastoma

Evaluating diagnostic value of 99mTc-CXCR4 scan in differentiation of high-grade and low-grade glioma

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230703058654N1
Enrollment
15
Registered
2023-10-22
Start date
2024-04-20
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glioblastoma. Malignant neoplasm of brain, unspecified

Interventions

The intervention groups include glioblastoma patients whose mass has been proven by imaging methods such as MRI. This evaluation is a diagnostic method using the single photon emission computed tomogr

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor
Nuclear Science and Technology Research Institute
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: The patient has been diagnosed with glioma based on MRI within the last month The patient is a candidate for surgical resection and has not undergone any type of anti-cancer treatment The patient's condition is stable for the scan The patient consents to the scan, and at the time of the scan Do not be pregnant or breastfeeding

Exclusion criteria

Exclusion criteria: Patients with multiple masses Patients who need emergency interventions after initial diagnosis Patients whose tumor cannot be operated Patients who do not consent to scan or surgery

Design outcomes

Primary

MeasureTime frame
The mean amount of radioactivity uptake in low-grade glioma patients. Timepoint: 3 hours after radiopharmaceutical administration. Method of measurement: SPECT/CT imaging.;The mean amount of radioactivity uptake in high-grade glioma patients. Timepoint: 3 hours after radiopharmaceutical administration. Method of measurement: SPECT/CT imaging.;Sensitivity of imaging to detect high-grade glioma. Timepoint: 3 hours after radiopharmaceutical administration. Method of measurement: SPECT/CT imaging and comparison with pathology results.;Sensitivity of imaging to detect low-grade glioma. Timepoint: 3 hours after radiopharmaceutical administration. Method of measurement: SPECT/CT imaging and comparison with pathology results.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. tahereh firuzyar

Shiraz University of Medical Sciences

firuzyar@sums.ac.ir+98 71 3612 5387

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026