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Comparing the effectiveness of calcitonin in reducing pain

Evaluating the efficacy of calcitonin in patients with discectomy: randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230702058645N3
Enrollment
44
Registered
2025-06-08
Start date
2025-06-10
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with discectomy surgery. Cervical disc disorder, unspecified

Interventions

Intervention 1: Intervention group: After surgery, inhaled calcitonin, brand name Nasocalcin (one puff (200 IU) per day) will be prescribed for 1 months. Intervention 2: Control group: After surgery,

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with a diagnosis of disc herniation (protrusion, extrusion, or detached fragment) based on MRI techniques Patients with complete and incomplete discectomy Patients older than 20 years of age Patient consent to participate in the study

Exclusion criteria

Exclusion criteria: History of surgery Trauma patients Patients with osteoporosis Patients with cancers Use of neuropsychiatric medications (due to possible impairment in pain perception compared to other people)

Design outcomes

Primary

MeasureTime frame
Pain intensity. Timepoint: Immediately and 4-months post-surgery. Method of measurement: Visual Analogue Scale.

Secondary

MeasureTime frame
The level of the patient's ability and function. Timepoint: Immediately and 4-months post-surgery. Method of measurement: Oswestry Disability Index (ODI).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPooyan Alizadeh

Ahvaz University of Medical Sciences

alizadeh-p@ajums.ac.ir+98 61 3320 4516

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026