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Impact of dexmedetomidine on radicular pain reduction

The efficacy of dexmedetomidine on radicular pain reduction during lumbar foraminal block: Randomized clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230702058645N1
Enrollment
124
Registered
2025-03-03
Start date
2025-02-19
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Radicular pain, Spine. Spondylosis

Interventions

Intervention 1: Intervention group: In the case group, 1 microgram of Dexmedetomidine per kilogram is administered along with Depomedrol. Depomedrol is administered as 40 mg for each facial foraminal

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients older than 20 years of age Failure of previous symptomatic treatment such as exercise, physiotherapy, and oral analgesics Patient consent to participate in the study

Exclusion criteria

Exclusion criteria: Patients with progressive weakness and muscle weakness Allergy to steroids Coagulopathy Steroid injection in the past 12 weeks Systemic infection Injection site infection Unstable mental and clinical condition Patients with spondylolisthesis Patient unwillingness to participate in the study Having a body mass index greater than 30 Patients with Cancer Patients with cardiovascular diseases Patients with hypertension

Design outcomes

Primary

MeasureTime frame
Oswestry Disability. Timepoint: Before, one month, two months, and three months post intervention. Method of measurement: The Oswestry Disability Index (ODI).;Pain intensity. Timepoint: Before, one month, two months, and three months post intervention. Method of measurement: Visual Analogue Scale.

Secondary

MeasureTime frame
Patient Satisfaction. Timepoint: Before, one month, two months, and three months post intervention. Method of measurement: Patient Satisfaction Index (PSI).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPooyan Alizadeh

Ahvaz University of Medical Sciences

Alizadeh-p@ajums.ac.ir+98 61 3320 4516

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026