Infertility. infertilefertility
Conditions
Interventions
Intervention 1: Control group: Standard triggering via the injection of human gonadotropic hormone (hCG). Intervention 2: Intervention group 1: dual triggering via hCG and Decapeptyl. Intervention 3:
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
24 Years to 42 Years
Inclusion criteria
Inclusion criteria: informed consent to participate in the study Age between 24-42 years old Body mass index of 19-27 The presence of POR (AFCI <7, AMH <1.5) Eligibility of the patient for IVF The absence of uterine abnormalities
Exclusion criteria
Exclusion criteria: Hypothalamic dysfunctions in the patient diabetes mellitus liver diseases heart diseases renal diseases epilepsy metabolic disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The number of good quality embryos. Timepoint: 3 days after fertilization. Method of measurement: High-quality cleavage stage embryos will have six cells or greater on day 3 and less than 10% fragmentation and symmetric blastomeres, according to the Istanbul consensus workshop. | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of retrieved oocytes. Timepoint: 36 hours after triggering. Method of measurement: All oocyte retrievals will be performed under transvaginal ultrasound guidance and will be counted using light microscopy.;The number of mature oocytes. Timepoint: 36 hours after triggering. Method of measurement: All oocyte retrievals will be performed under transvaginal ultrasound guidance and the number of mature oocytes will be counted using light microscopy.;The number of clinical pregnancies. Timepoint: the presence of gestation sac two weeks after a positive hCG blood test. Method of measurement: ultrasound scan.;Implantation rate. Timepoint: at 6–7 weeks of pregnancy. Method of measurement: Implantation rate is calculated from the number of gestational sacs with a visible fetal heart on ultrasound scan divided by the total number of transferred embryos. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAliyeh Ghasemzadeh
Tabriz University of Medical Sciences
Outcome results
None listed