Type 2 diabetes. Diabetes mellitus due to underlying condition
Conditions
Interventions
Intervention group: Vitamin C chewable tablets. The dose of ascorbic acid is 500 mg once a day..
Sponsors
Shahre-kord University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: 30-65 years old Not using corticosteroids and anticoagulants in the last month Not using oral contraceptives in the last month Not smoking People who have not received vitamin C supplements at least 3 months before the test People who are not professional athletes People are placed in two equal groups in terms of receiving metformin/insulin Patients should not take melatonin, aspirin, D3, or omega-3 during the study
Exclusion criteria
Exclusion criteria: Non-cooperation of patients to participate in the study The presence of congenital cognitive and anxiety diseases Incomplete completion of the questionnaire People taking combined oral blood sugar-lowering drugs such as Synoripa tablets ... people taking drugs related to severe depression (bipolar).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean scores of cognitive symptoms. Timepoint: At the beginning of the study and after three months after starting to use ascorbic acid or placebo. Method of measurement: Addenbrooke's Cognitive Examination.;Depression change score. Timepoint: At the beginning of the study and after three months after starting to use ascorbic acid or placebo. Method of measurement: Depression- Anxiety- Stress Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Level of Interleukin 6 in the serum. Timepoint: At the beginning of the study and after three months after starting to use ascorbic acid or placebo. Method of measurement: Real-time PCR technique. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactReihaneh Sadeghian
Shahre-kord University of Medical Sciences
Outcome results
None listed