Acute hemodynamic changes using Ultra-Sonographic Cardiac Output Monitoring of mechanically ventilated children with acute respiratory distress syndrome during and after the recruitment maneuver in two different methods

Evaluation of the acute hemodynamic changes using Ultra-Sonographic Cardiac Output Monitoring of mechanically ventilated children with acute respiratory distress syndrome during and after the recruitment maneuver in two different methods

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230701058628N3

Enrollment

Registered

2025-01-24

Start date

2025-01-20

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Viral infection. Condition 2: Acute lower respiratory infection. Condition 3: Acute respiratory distress syndrome. Condition 4: Congenital cyanotic heart diseases. Viral infection of unspecified site Unspecified acute lower respiratory infection Acute respiratory distress syndrome Other specified congenital malformations of heart

Interventions

Intervention 1: Intervention group: Patients are randomly divided into two groups, and in one group, maneuver 1 is performed on the first day and maneuver 2 is performed on the second day, and in the

Eligibility

Sex/Gender

All

Age

1 Months to 18 Years

Inclusion criteria

Inclusion criteria: Age 1 month to18 years Acute respiratory distress syndrome Requiring mechanical ventilation Requiring maneuver Pediatric intensive care unit admission

Exclusion criteria

Exclusion criteria: Presence of bradycardia or hypotension Need to increase the dose of inotropes in the last 6 hours Cardiopulmonary resuscitation within 24 hours before performing any maneuver Severe pleural effusion Untreated pneumothorax History of cyanotic congenital heart disease

Design outcomes

Primary

Measure	Time frame
Mean arterial blood pressure. Timepoint: Zero, 5, 10 and 30 minutes from the start of the maneuver. Method of measurement: Blood pressure monitor.;Blood oxygen saturation. Timepoint: Zero, 5, 10 and 30 minutes from the start of the maneuver. Method of measurement: Pulse oximeter.;Heart rate. Timepoint: Zero, 5, 10 and 30 minutes from the start of the maneuver. Method of measurement: Cardiac monitoring.	—

Measure

Time frame

Mean arterial blood pressure. Timepoint: Zero, 5, 10 and 30 minutes from the start of the maneuver. Method of measurement: Blood pressure monitor.;Blood oxygen saturation. Timepoint: Zero, 5, 10 and 30 minutes from the start of the maneuver. Method of measurement: Pulse oximeter.;Heart rate. Timepoint: Zero, 5, 10 and 30 minutes from the start of the maneuver. Method of measurement: Cardiac monitoring.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Marziyeh Taji Eshkaftaki

Mazandaran University of Medical Sciences

marziyehtaji1995@gmail.com+98 11 3334 2334

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026