Effect of bromelain and curcumin supplement in knee osteoarthritis. Osteoarthritis of knee, unspecified
Conditions
Interventions
Intervention 1: Intervention group 1: The first group, consisting of 20 patients, will receive 200 mg of Celecoxib once daily for one month. Intervention 2: Intervention group 2:The second group, also
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: All patients over 18 years old and suffer from non-infectious knee osteoarthritis
Exclusion criteria
Exclusion criteria: Sensitivity to pineapple ,celery, carrot and fennel Haemophilia Who take two antiplatelet drugs or one antiplatelet drug and one anticoagulant drug Suspicion of infection severe kidney impairment ( GFR< 30) severe liver impairment (child Pugh C and B ) Pregnant and breastfeeding women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of knee inflammation. Timepoint: The first week, the end of the second week, and the end of the month. Method of measurement: Measurement by WOMAC scale and Visual Analogue Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Examination of the inflammatory process and pain level. Timepoint: Week one, end of week 2 , and end of the month. Method of measurement: Evaluation of factors in the knee functional questionnaire and visual analogue scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmir Rezazadeh
Iran University of Medical Sciences
Outcome results
None listed