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the effect of chitosan/aloe vera gel loaded with zinc oxide nanoparticles in treatment of wounds after gynecological surgeries

Investigating the effect of chitosan/aloe vera gel loaded with zinc oxide nanoparticles in treatment of wounds after gynecological surgeries: a randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230629058615N2
Enrollment
66
Registered
2024-05-08
Start date
2024-06-21
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

wounds after gynecological surgeries (such as caesarean section, hysterectomy, etc.). Disruption of cesarean delivery wound

Interventions

Intervention 1: Intervention group: People receiving Chitosan Aloe Vera Zinc Oxide Gel. After entering the study, 33 patients with post-surgical wounds were randomly assigned to the Treatment group ba

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to No maximum

Inclusion criteria

Inclusion criteria: Women who have undergone any gynecological surgery (including surgery related to ovarian cysts, hysterectomy, etc.) or cesarean section and 72 hours have passed since their operation. Women diagnosed with postoperative surgical wounds Women who are able to understand and comply with the study procedures and follow-up requirements Women who are 15 years of age or older Mothers unable or unwilling to breastfeed their infants

Exclusion criteria

Exclusion criteria: Being allergic to any of chitosan, aloe vera and zinc oxide nanoparticles Patients with severe renal failure (GFR less than 30) Patients with severe liver failure (Child Pugh score B-C) Taking certain drugs (such as glucocorticoids, anticoagulants, immunosuppressants) while using the study gel Women who are able and willing to breastfeed.

Design outcomes

Primary

MeasureTime frame
Enhancement of wound condition. Timepoint: End of week 1 and week 4. Method of measurement: Measurement by "Patient and Observer Scar Evaluation Scale" score.

Secondary

MeasureTime frame
Examining the inflammatory process and tissue healing. Timepoint: End of week 1 and week 4. Method of measurement: Evaluation of five healing factors including redness, edema, ecchymosis, secretion, and overlap of wound edges.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSahand Soudi

Iran University of Medical Sciences

sahandsoudi@gmail.com+98 21 4460 6181

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026