Osteoarthritis. Osteoarthritis of knee
Conditions
Interventions
Intervention 1: Intervention group: 35 patients receiving capsules containing colchicum, ashwagandha and mustic gum twice a day for 42 days. Intervention 2: Control group: 35 patients receiving capsul
Sponsors
Kerman University of Medical Sciences
Eligibility
Sex/Gender
All
Age
45 Years to 70 Years
Inclusion criteria
Inclusion criteria: Age of 45-75 years old Diagnosis of knee osteoarthritis based on the criteria of the American College of Rheumatology, which is confirmed by a rheumatology specialist. The presence of moderate knee pain within 24 hours based on linear-visual pain scale (VAS) between 3.5 and 7.5 cm. Completing the inform consent form
Exclusion criteria
Exclusion criteria: Pregnancy or breastfeeding Lack of physical and mental ability to answer questions Occurrence of debilitating disease during treatment History of allergy to herbal medicines use of alcohol or drug abuse History of systemic diseases such as heart failure, kidney failure and uncontrolled blood pressure Routine use of oral analgesic (except 500 mg oral acetaminophen daily) Consuming nutritional and medicinal supplements on a regular and daily basis Intra-articular injection of corticosteroid drugs during the last six months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Knee pain intensity. Timepoint: at the begining of intervention and 21 and 42 days after the intervention. Method of measurement: Western Ontario and McMaster Universities Arthritis Index (WOMAC) questionnaire, visual analogue scale (VAS) questionnaire.;Morning stiffness of knee. Timepoint: at the begining of intervention and 21 and 42 days after the intervention. Method of measurement: Western Ontario and McMaster Universities Arthritis Index (WOMAC) questionnaire.;Physical performance. Timepoint: at the begining of intervention and 21 and 42 days after the intervention. Method of measurement: Western Ontario and McMaster Universities Arthritis Index (WOMAC) questionnaire.;Heel to thigh distance. Timepoint: at the begining of intervention and 21 and 42 days after the intervention. Method of measurement: Western Ontario and McMaster Universities Arthritis Index (WOMAC) questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHossein Karegar-Borzi
Kerman University of Medical Sciences
Outcome results
None listed