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Investigating and comparing effect of low dose Atropine and minus lens therapy on intermittent exotropia.

Investigating and comparing the effect of 0.05%Atropine with minus lens therapy method on angle and control of deviation in children with intermittent exotropia.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230626058588N1
Enrollment
42
Registered
2023-08-12
Start date
2023-07-06
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intermittent exotropia. Intermittent alternating exotropia

Interventions

Intervention 1: Intervention group: Atropine 0.05% is an anticholinergic drug and the first intervention. In order to process this drop, we dilute 0.5% atropine made by Sina Daru Company 10 times with

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 8 Years

Inclusion criteria

Inclusion criteria: Full term children with intermittent exotropia.

Exclusion criteria

Exclusion criteria: Unilateral or bilateral amblyopia history of epilepsy or seizures and asthma history of drug sensitivity history of strabismus surgery presence of vertical deviation more than 5 prisms unwillingness to continue this study

Design outcomes

Primary

MeasureTime frame
Angle of deviation, control of deviation. Timepoint: Before, one month and 3 months after intervention. Method of measurement: Angle of deviation: prism bar and cover test. Control of deviation: 3 and 6 scale criteria.

Secondary

MeasureTime frame
Stereopsis. Timepoint: Before, one month and 3 months after intervention. Method of measurement: Stereopsis: Titmus.;Suppression. Timepoint: Before, one month and 3 months after intervention. Method of measurement: 4 dots Worth test.;Accommodation response. Timepoint: Before, one month and 3 months after intervention. Method of measurement: MEM dynamic retinoscopy.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarzaneh Dehghanian Nasrabadi

Iran University of Medical Sciences

Fdehghanian1991@gmail.com+98 21 2222 7124

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026