The effect of oxygenation on patients under mechanical ventilation

The effect of nasopharyngeal oxygenation on the outcome of patients undergoing mechanical ventilation with an endotracheal tube (ETT)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230626058586N9

Enrollment

Registered

2024-12-13

Start date

2025-01-20

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Need for sedation. Restlessness and agitation

Interventions

Intervention 1: Intervention group: 40 patients on mechanical ventilation plus oxygen via nasal cannula. Intervention 2: Control group: 40 patients under mechanical ventilation.

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: The patient is under mechanical ventilation Have stable vital signs

Exclusion criteria

Exclusion criteria: Mechanical ventilation lasts more than ten days

Design outcomes

Primary

Measure	Time frame
Need for sedation. Timepoint: The first day after intubation and the end of the third day of intubation. Method of measurement: Richmond Agitation-Sedation Scale (RASS).;Patient's level of consciousness. Timepoint: The first day after intubation and the end of the third day of intubation. Method of measurement: Glasgow Coma Scale (GCS).;Mortality. Timepoint: The first day after intubation and the end of the third day of intubation. Method of measurement: Observe the loss of vital signs.;Ventilator-associated pneumonia (VAP). Timepoint: The first day after intubation and the end of the third day of intubation. Method of measurement: Positive respiratory culture for pulmonary infection.	—

Measure

Time frame

Need for sedation. Timepoint: The first day after intubation and the end of the third day of intubation. Method of measurement: Richmond Agitation-Sedation Scale (RASS).;Patient's level of consciousness. Timepoint: The first day after intubation and the end of the third day of intubation. Method of measurement: Glasgow Coma Scale (GCS).;Mortality. Timepoint: The first day after intubation and the end of the third day of intubation. Method of measurement: Observe the loss of vital signs.;Ventilator-associated pneumonia (VAP). Timepoint: The first day after intubation and the end of the third day of intubation. Method of measurement: Positive respiratory culture for pulmonary infection.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMarziye Shahrabi

Shahid Beheshti University of Medical Sciences

shahrabimarzieh@gmail.com+98 912 183 6552

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026