Condition 1: anxiety. Condition 2: depression. Anxiety disorder due to known physiological condition Other depressive episodes
Conditions
Interventions
Intervention 1: Intervention group: Agomelatine (25-50mg). Intervention 2: Intervention group: Sertraline (50-200 mg).
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Confirmation of PNES diagnosis by neurologist and psychiatrist Not suffering from mental disability and pregnancy Age range between 18-65 years Patient satisfaction
Exclusion criteria
Exclusion criteria: Patient's lack of consent to continue participating in the study Confirmation of neurological disorder or other major disorders in addition to anxiety and depression during study Not coming for a follow-up visit.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression. Timepoint: before the intervention and one month, two months and three months after the intervention. Method of measurement: Hamilton questionnaire.;Anxiety. Timepoint: before the intervention and one month, two months and three months after the intervention. Method of measurement: Hamilton questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Seizure attacks. Timepoint: before the intervention and one month, two months and three months after the intervention. Method of measurement: EEG. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRoya Vaziri Harami
Shahid Beheshti University of Medical Sciences
Outcome results
None listed