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The effect of cannabidiol on sleep quality and pain reduction

The Comparative Evaluation of the Impact of Cannabidiol Administration Versus Non-Administration on Sleep Quality and Pain Outcomes in Patients Undergoing Intermediate Elective Abdominal Surgery

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230626058586N12
Enrollment
50
Registered
2026-01-03
Start date
2026-02-20
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Sleep quality. Condition 2: Postoperative Pain. Other sleep disorders not due to a substance or known physiological condition Other acute postprocedural pain

Interventions

Intervention 1: Intervention group: Administration of an oral solution (as drops) of cannabidiol at a concentration of 100 mg/mL and a dose of 25 mg (equivalent to 0.25 mL of the solution) will be giv

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients Undergoing Intermediate Elective Abdominal Surgery Age between 18 and 65 years American Society of Anesthesiologists (ASA class) II/III Patient satisfaction

Exclusion criteria

Exclusion criteria: Addicted patients Patients with a history of psychiatric disorders and sleep disturbances

Design outcomes

Primary

MeasureTime frame
Post operative sleep quality. Timepoint: Once after the intervention (after recovery). Method of measurement: Using the Richards-Campbell Sleep Questionnaire (RCSQ).;Post operative pain. Timepoint: At four time points: namely 1 hour, 2 hours, 4 hours, and 8 hours after the intervention. Method of measurement: Visual Analog Survey Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKasra Karvandian

Tehran University of Medical Sciences

karvandian@tums.ac.ir+98 21 6658 1625

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026