Decreased mean arterial blood pressure. Hypotension due to drugs
Conditions
Interventions
Intervention 1: Intervention group1: Administration of isoflurane 1.2-1.6 mcg/kg. Intervention 2: Intervention group2:Administration of sevoflurane 1.5 mcg/kg.
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age range 18-65 years American Society of Anesthesiologists (ASA) Group II/III Patient satisfaction
Exclusion criteria
Exclusion criteria: Baseline mean arterial blood pressure less than 60 mm Hg Cardiovascular or peripheral vascular disease (such as diabetic vasculopathy or Raynaud's disease) Taking medications that may affect sympathetic or parasympathetic tone (such as beta blockers or anticholinergic) Having any neurological or psychiatric illness, including a history of substance abuse, anxiety or depression
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean arterial blood pressure. Timepoint: Invasive blood pressure will be measured continuously during surgery. Non-invasive blood pressure will be measured at 5-minute intervals. Method of measurement: Arterial line insertion for invasive measurement and manometer cuff for non-invasive measurement. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactKasra Karvandian
Tehran University of Medical Sciences
Outcome results
None listed