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Effect of buffered anesthetics in odontogenic infections

Comparison of buffered with standard local anesthetics in odontogenic infections: a randomized controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230622058557N2
Enrollment
70
Registered
2023-07-04
Start date
2019-03-11
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Odontogenic Infection: Defined as inflammation originating within a tooth or closely related to the surrounding structures presenting as periapical inflammation in the form of acute periapical periodontitis or a periapical abscess with or without extensions into adjacent facial planes. Condition 2: Odontogenic Infection: Defined as inflammation originating within a tooth or closely related to the surrounding structures presenting as periapical inflammation in the form of acute peria

Interventions

Intervention 1: Intervention group: Group A. This group received buffered local anesthesia by adding 0.18 ml of 8.4 percent sodium bicarbonate solution to 1.8ml 2 % Lignocaine with 1:100,000 adrenali

Sponsors

Armed Forces Institute of Dentistry
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patient between 18 to 70 years that have Odontogenic maxillofacial infection surrounding any tooth. Lack of sensitivity to local anesthetics Patients having acute abscess of any tooth Patients having acute periapical periodontitis leading to granuloma formation Patients having physical status 1 and 2 according to American Society of Anesthesiologists(ASA) classification

Exclusion criteria

Exclusion criteria: Patients with systemic diseases for which injections of lignocaine with adrenaline are contraindicated will be excluded from the study Anesthesia allergy or drug abuse history

Design outcomes

Primary

MeasureTime frame
Pain Assessment: Pain will be determined by the patient before and after injection using VAS Pain score. It is a 10 cm long scale with 0 marking indicating no pain to 10 marking as worst pain possible. Timepoint: Before and immediately after local anesthetic injection. Method of measurement: Visual Analog Pain Score.;Efficacy of Anesthesia: Determined by the onset of anesthesia i.e. the first feeling of numbness in the region of the teeth anaesthetized checked by inserting straight probe in the gingival sulcus of the involved region. Timepoint: Immediately after injection is administered with 30 seconds intervals . Method of measurement: Seconds.

Countries

Pakistan

Contacts

Public ContactSyeda Mahnoor Fatima

Armed Forces Institute of Dentistry affiliated with National University of Medical Sciences

mahnooorbukhari@gmai.com+92 335 5508126

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026