Comparison the effect of Shirvan herbal ointment and glucantim drug on the cutaneous leshmaniasis wounds.

Comparison the therapeutic effect of Shirvan herbal ointment with glucantim drug on the cutaneous leshmaniasis wounds.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230621058552N1

Enrollment

Registered

2023-06-28

Start date

2023-08-23

Completion date

Unknown

Last updated

2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Leishmaniasis. Body mass index (BMI) pediatric, 85th percentile to less than 95th percentile for age

Interventions

Intervention group: In the case of 10 patients with a minimum lesion of less than 2 cm, Shirvan herbal ointment (twice a day) for one lesion and glucantim drug (intralesional injection of 5 ml weekly

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Confirmed cases of urban leishmaniasis. Informed consent signed The diameter of the lesion < 2 cm. Lesions only in hands and feet.

Exclusion criteria

Exclusion criteria: Pregnant or lactating women, Cardiovascular patients, Lesions on joints and cartilage, The diameter of the lesions> 2 cm, Illness period of more than 8 weeks, Sperotrichoid and chronic lesions, Using any type of treatment for leishmaniasis in the last month. Participation in any type of project in the last 2 months

Design outcomes

Primary

Measure	Time frame
At each follow-up, the size of erythema, induration, ulceration and scar (largest diameter times its perpendicular diameter in milliliters) will be recorded. Evaluation of clinical recovery based on the complete re-epithelialization of the lesions as the main measure of treatment effect is performed in the last injection session and the follow-up period (1, 4 weeks and 6 months) on each of the treated lesions. Timepoint: The measurement of the lesion is at the beginning of the study (before the start of the intervention) and 1, 4 weeks and 6 months after the start of taking Shirvan herbal ointment and glucantim medicine. Method of measurement: The lesion surface will be measured using caliper software.	—

Measure

Time frame

At each follow-up, the size of erythema, induration, ulceration and scar (largest diameter times its perpendicular diameter in milliliters) will be recorded. Evaluation of clinical recovery based on the complete re-epithelialization of the lesions as the main measure of treatment effect is performed in the last injection session and the follow-up period (1, 4 weeks and 6 months) on each of the treated lesions. Timepoint: The measurement of the lesion is at the beginning of the study (before the start of the intervention) and 1, 4 weeks and 6 months after the start of taking Shirvan herbal ointment and glucantim medicine. Method of measurement: The lesion surface will be measured using caliper software.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Aghaei

Esfahan University of Medical Sciences

maryam.aghaei2008@gmail.com+98 31 3339 0100

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026