Condition 1: Periodontitis. Condition 2: Rheumatoid arthritis. Gingivitis and periodontal diseases Other rheumatoid arthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Confirmed RA Having at least 10 teeth No definitive diagnosis of COPD (patients without airway obstruction with FEV1/FVC = 0.7) Having periodontitis stage II-IV and grade B
Exclusion criteria
Exclusion criteria: fever history of adult-onset or infectious diseases history of lung-reducing surgeries history of lung transplantation or pneumonectomy history of any periodontal treatment in the last 6 months or antibiotic use in the last 3 months smoking history of any inflammatory disease except RA and periodontitis history of diabetes pregnancy or breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Forced Expiratory Volume in one second/ Forced Vital Capacity (FEV1/FVC). Timepoint: Before intervention, three months after intervention, six months after intervention. Method of measurement: Spirometry test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Erythrocyte Sedimentation Rate(ESR). Timepoint: Before intervention, three months after intervention, six months after intervention. Method of measurement: Blood test.;C_reactive protein (CRP). Timepoint: Before intervention, three months after intervention, six months after intervention. Method of measurement: Blood test.;Creactive protein/Albumin (CRP/ALB). Timepoint: Before intervention, three months after intervention, six months after intervention. Method of measurement: Blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Yazd University of Medical Sciences