Evaluation the effect of the adjunctive use of red CoQ10 on the results of non-surgical periodontal treatment

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230615058492N1

Enrollment

Registered

2023-08-05

Start date

2023-09-23

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic periodontitis. Chronic periodontitis

Interventions

Intervention 1: Intervention group: 100 mg red CoQ10 soft gel contains coenzyme Q10, vitamin E and vitamin A. The patient should take one daily with water or food orally for 6 weeks. This substance is

Eligibility

Sex/Gender

All

Age

25 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. The amount of clinical attachment loss is 3 mm or more The age of the patient is between 25-60 3. The patient should be systemically healthy (such as not suffering from diabetes, high blood pressure or liver problems)

Exclusion criteria

Exclusion criteria: History of periodontal treatment during the last 6 months Presence of disease or systemic conditions that interfere with wound healing. Pregnant or lactating patient smoking The patient is undergoing radiotherapy or chemotherapy Taking drugs that affect the periodontium, such as anticonvulsants, calcium channel blockers Taking blood lipid-lowering drugs that reduce Coenzyme Q10, such as statins ( lovastatin and atorvastatin) Taking vitamin A, vitamin E and Coenzyme Q10 supplements during the last three months Taking warfarin or clopidogrel because some studies indicate the interaction of Coenzyme Q10 with anticoagulant drugs.

Design outcomes

Primary

Measure	Time frame
Probing depth. Timepoint: At the beginning of the study and 6 weeks after the start of red CoQ10 consumption. Method of measurement: Williams periodontal probe.	—

Secondary

Measure	Time frame
Clinical attachment loss. Timepoint: At the beginning of the study and 6 weeks after the start of red CoQ10 consumption. Method of measurement: Williams periodontal probe.;Bleeding on probing. Timepoint: At the beginning of the study and 6 weeks after the start of red CoQ10 consumption. Method of measurement: Williams periodontal probe.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactsusan kabirirad

Yazd University of Medical Sciences

kabirirad.ho@gmail.com+98 35 3625 5881

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026