Acute agitation. Restlessness and agitation
Conditions
Interventions
Intervention 1: Intervention group: Ketamine Group. Intervention 2: Intervention group: Haloperidol group.
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: All acutely agitated patients enrolled in the study. Treatable causes such as hypoxia and hypoglycemia were evaluated in if present, treated.
Exclusion criteria
Exclusion criteria: Any sensitivity to ketamine or haloperidol, past medical history of dissection or myocardial infarction, or QT prolongation lead to exclude from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Agitation control based on RASS score. Timepoint: After admission, 30 and 60 minutes after the drug administration. Method of measurement: Agitation control will be assess by Richmond Agitation and Sedation Score. | — |
Secondary
| Measure | Time frame |
|---|---|
| The sedation time based on minutes, the side effects of drugs include apnea, nausea and vomiting, need for intubation, tachycardia, hypertension, tachycardia, QT prolongation, tachycardia, and dysrhythmias. Timepoint: At admission and 30 and 60 minutes after drug administration. Method of measurement: Any side effects and time to sedation(minutes) will document. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactElnaz Vafadar Moradi
Mashhad University of Medical Sciences
Outcome results
None listed