Gastroesophageal reflux. Gastro-esophageal reflux disease
Conditions
Interventions
Intervention 1: Intervention group: All patients will take the same drugs prescribed by the internal specialist, and in addition, the intervention group will take coriander seed capsules (500 mg capsu
Sponsors
Ghoum University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Age 18 to 60 Outpatients with history of at least 4 weeks of major reflux symptoms in the last 3 months Informed consent to participating in the study Consent to avoiding out of protocol medication
Exclusion criteria
Exclusion criteria: History of gastrointestinal cancers in the patient and first degree relatives History of esophageal, abdominal or stomach surgery Suffering from diabetes, acute peptic ulcer, achalasia and acute gastrointestinal diseases, gastrointestinal bleeding, iron deficiency anemia, anorexia, persistent vomiting, unexplained weight loss, pregnancy Taking aspirin and warfarin/taking herbal medicines one month before the study Impotency and sperm production disorders/severe amnesia Presence of dysphagia and odynophagia History of obstructive diseases(kidney and gallbladder stone)\amenorrhea or oligomenorrhea
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptoms of gastro-esophageal reflux disease. Timepoint: At the beginning of the stydy, the end of the third week and the end of the sixth week. Method of measurement: Frequency Scale for the Symptoms of GERD (FSSG)Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of quality of life in reflux and dyspepsia. Timepoint: At the beginning of the study,the end of the third week and the end of the sixth week. Method of measurement: Quality of Life in Reflux and Dyspepsia(QOLRAD)Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Shamsian
Ghoum University of Medical Sciences
Outcome results
None listed