Effect of PRP and methylprednisolone injection in patients with partial rotator cuff tear

A comparative study on the effects of subacromial injections of platelet-rich plasma and methylprednisolone for improving range of motion, reducing pain, and enhancing function in patients with partial rotator cuff tears

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230608058415N1

Enrollment

100

Registered

2024-05-08

Start date

2024-05-29

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Partial rotator cuff tear. Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder

Interventions

Intervention 1: Intervention group: In the first intervention group, a subacromial injection of 40 milligrams of methylprednisolone is performed under sonography guidance. Then, simple shoulder tests,

Eligibility

Sex/Gender

All

Age

30 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with partial thickness rotator cuff tear and reduced shoulder range of motion Patient does not have any contraindication for shoulder injection Age more than 30

Exclusion criteria

Exclusion criteria: Patients with previous shoulder surgery and injection Patients with frozen shoulder Patients with shoulder fracture Other pathologies induce shoulder pain (in examination and radiology) Patients with full thickness rotator cuff tear

Design outcomes

Primary

Measure	Time frame
Shoulder function. Timepoint: Before injection, 3 & 6 months after injection. Method of measurement: Constant-Merely.	—

Secondary

Measure	Time frame
Shoulder pain. Timepoint: Before injection, 3 & 6 months after injection. Method of measurement: Visual Analogue Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Pourfarzaneh

Tehran University of Medical Sciences

mpourfarzaneh50@gmail.com+98 21 6119 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026