Recurrent Aphthous Stomatitis. Recurrent oral aphthae
Conditions
Interventions
Intervention 1: "Intervention Group1:" Razi tablet is an herbal medicine produced by the knowledge-based pharmaceutical company Niak for the treatment of lumbar disc pain, sciatica, joint pain caused
it will be prescribed with a dose of 2-4 tablets per day for one month. Intervention 2: "Intervention group2:" Colchicine, a drug extracted from the Colchicum plant, is one of the medications used to
Sponsors
Gorgan University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All patients with recurrent oral ulcers (those who had painful, round lesions with clear margins in any part of the oral cavity)
Exclusion criteria
Exclusion criteria: History of treatment for cancer in the past 3 months Severe systemic disease or autoimmune disease Breastfeeding and pregnancy Use of any treatment for oral ulcer healing Use of mouthwash or topical gel for ulcer treatment up to 1 week before the start of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oral aphthous count. Timepoint: 7, 14, and 21 days after starting Razi and colchicine tablets. Method of measurement: counting the number of aphthous.;Oral aphthous size. Timepoint: 7, 14, and 21 days after starting Razi and colchicine tablets. Method of measurement: ruler.;Visual analog scale. Timepoint: 7, 14, and 21 days after starting Razi and colchicine tablets. Method of measurement: Qualitative questionnaire of the Visual Analog Scale (VAS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFateme Rostami
Gorgan University of Medical Sciences
Outcome results
None listed