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Efficacy of haloperidol prophylaxis on Delirium

Examining the effects of haloperidol prophylaxis on the incidence and severity of Delirium in patients after thoracotomy and major laparotomy

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230607058400N3
Enrollment
164
Registered
2024-12-09
Start date
2024-12-15
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Delirium. Postoperative delirium

Interventions

Intervention 1: Intervention group: Haloperidol prophylaxis, according to the existing guideline, is administered at a dose of 0.5 mg three times daily from the day of surgery until 72 hours postopera

Sponsors

Gorgan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to No maximum

Inclusion criteria

Inclusion criteria: Age 40 and above Major thoracic or abdominal surgery Patient consent

Exclusion criteria

Exclusion criteria: Patient's unwillingness to continue the study Patients with a history of heart disease Patients with a history of prior neurological or psychiatric disorders Having an addiction Previous use of psychiatric medication

Design outcomes

Primary

MeasureTime frame
The incidence of delirium in patients after surgery. Timepoint: Daily assessments until the patient's hospitalization period ends. Method of measurement: CAM-ICU Scale.

Secondary

MeasureTime frame
Severity of delirium in patients. Timepoint: Daily assessments until the patient's hospitalization period ends. Method of measurement: Delirium Rating Scale (DRS).;Duration of postoperative delirium in patients. Timepoint: Daily assessments until the patient's hospitalization period ends. Method of measurement: Checklist for recording the length of hospitalization.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Aghaee

Gorgan University of Medical Sciences

zahra.aghaeemed@gmail.com+98 911 390 3424

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026