Obsessive Compulsive Disorder.
Conditions
Interventions
Intervention 1: Intervention group: Transcranial Alternating Current Stimulation will be performed in 4 weeks, 2 days a week for 20 minutes with a frequency of 40 Hertz and a current of 2 milliamps. E
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: According to the DSM-5 diagnostic and statistical manual of obsessive-compulsive disorder Age between 18 and 60 years Obtaining a score of 16 (patients with severe and moderate disease conditions) on the Yale Brown scale Absence of other psychiatric and neurological diseases Ability to perform behavioral tests and answer questionnaires by the patient Signing a written consent form by the patient
Exclusion criteria
Exclusion criteria: Inconsistency with study inclusion criteria Patient's unwillingness to participate in the study Patient's inability to perform diagnostic tests Inability to receive tACS due to metal implants, or history of seizures, or history of trauma to the head, or history of neurosurgery Participants who have anasthenia gravis, a pacemaker, a mechanical heart valve, a mechanical implant such as an aneurysm clip, a hip replacement, or any other piece of metal accidentally inserted into their body Any current significant medical condition Serious risk of suicide A female subject who is pregnant or of childbearing potential, sexually active, not using reliable contraception, or breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Obsessive-compulsive symptom score in the Yale Brown Questionnaire. Timepoint: Examining the amount of obsession compulsive symptoms before starting the study and at the end of the first, second and third weeks and Also, at the end of the intervention (end of the fourth week). Method of measurement: Yale Brown Questionnaire:It was created by "Wayne K. Goodman" and his colleagues in 1989 in the United States. Yale Brown Obsessive Compulsive Psychology Test (YBOCS) is the most reliable theoretical test for diagnosing obsessive compulsive disorder in adults, which is used in counseling and psychology centers. This test is a self-report tool to measure obsessive thoughts and obsessive/compulsive behaviors. This questionnaire has 10 statements with a Likert scoring system (from 0 none to 4 very severe), of which 5 options are intended to evaluate obsessive thoughts and 5 other options are considered to evaluate practical obsessions. The two subscales in this questionnaire are: (a) "Obsessive thoughts": including aggressive obsessions, consuming obsessions, sexual obsessions, hoarding or collecting obsessions, religious obsessions, symmetry and order obsessions, miscellaneous obsessions, and physical obsessions, and (b) "Compulsions": including washing and cleaning, checking, repetition rituals, obsessive behaviors related to counting, order and order, hoarding , and various obsessive behaviors. This test can be performed individually or in groups for people 14 years old and above. On average, this test takes about 10 minutes to complete. | — |
Secondary
| Measure | Time frame |
|---|---|
| Beck depression questionnaire score. Timepoint: Checking the level of depression before the study and at the end of the first, second, third and fourth weeks (the end of the study). Method of measurement: Beck Depression Questionnaire:The Beck Depression Questionnaire was first compiled by Beck et al. in 1961. It was revised in 1971 and published in 1978.In general, the content of this questionnaire is the semiotics of depression, but it emphasizes more on the cognitive content. This questionnaire is a type of self-assessment test and can be completed in five to ten minutes. The test items consist of a total of 21 items that are related to different symptoms. The subjects must answer it on a four-point scale from zero to three. Areas such as sadness, pessimism, feelings of helplessness and failure, feelings of guilt, sleep disturbance, loss of appetite, self-loathing, etc. constitute substances. In this way, 2 items are related to affection, 11 items are related to cognition, 2 items are related to obvious behaviors. 5 items are related to physical symptoms and 1 item is related to interpersonal semiotics. Accordingly, this scale determines different degrees of depression from mild to very severe, and its scores range from a minimum of 0 to a maximum of 63. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactElmira Zeinoddini meymand
Islamic Azad University
Outcome results
None listed