The effect of dexmedetomidine as adjuvant analgesia on postoperative delirium, and perioperative and postoperative arrythmia and hemodynamics in opium user patients undergoing open heart surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230603058373N1

Enrollment

Registered

2023-12-14

Start date

2023-12-12

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: post operative delirium. Condition 2: cardiac surgery complications. Other delirium Unspecified complication of cardiac and vascular prosthetic device, implant and graft

Interventions

Intervention 1: Intervention group: In the intervention group, in addition to the common anesthesia protocol, loading dose: 6 mcg/kg/hr intravenous dexmedetomidine with maintenance drip of 0.2 mcg/kg/

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: history of opium addiction candidate for elective open heart surgery

Exclusion criteria

Exclusion criteria: weight2h history of cerebral stroke Impaired level of consciousness history of heart failure kidney failure or history of dialysis

Design outcomes

Primary

Measure	Time frame
Delirium. Timepoint: daily. Method of measurement: confusion assessment method.;Arrhythmia. Timepoint: perioperative and postoperative. Method of measurement: checklist.	—

Secondary

Measure	Time frame
Postoperative pain. Timepoint: every 4h. Method of measurement: visual analog scale.;Cognitive function. Timepoint: preoperative and postoperative. Method of measurement: mini mental state exam.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Foroozeshfard

Semnan University of Medical Sciences

mff45@yahoo.com31420000-023

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026