Investigating the effect of tranexamic acid in preventing dry socket syndrome

Investigating the effect of tranexamic acid in preventing dry socket syndrome following surgical extraction of the impacted third molar of the mandible

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230603058370N1

Enrollment

Registered

2023-06-20

Start date

2023-06-20

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry socket. Other diseases of jaws

Interventions

Intervention 1: All patients undergo wisdom tooth extraction surgery by one person. The type of cut in all operations is similar and buccal flap type with distobuccal releasing, along with sulcular cu

Eligibility

Sex/Gender

All

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Age between 18 and 35 years the third molar teeth of the mandible are embedded bilateral and placed in class I, II, III, level A, B, and C based on the classification of Paul and Gray Gori require surgical tooth extraction.

Exclusion criteria

Exclusion criteria: Users of exogenous corticosteroids the presence of systemic disorders respiratory and digestive diseases pregnant women and lactating mothers systemic fungal infections acute infections and active or silent tuberculosis

Design outcomes

Primary

Measure	Time frame
Occurrence or absence of dry socket syndrome. Timepoint: Two or three days after surgery on both intervention and control sides. Method of measurement: Evaluation through clinical observation by maxillofacial surgeon.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHassan Mesgari

Islamic Azad University

kmesgari@gmail.com+98 21 2256 4571

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026