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The effect of administering high doses of intravenous vitamin C in severe traumatic brain injuries

The effect of administering high doses of intravenous vitamin C in severe traumatic brain injuries

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230530058344N1
Enrollment
69
Registered
2023-06-08
Start date
2023-06-22
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

severe traumatic brain injuries. Multiple injuries of head

Interventions

Intervention 1: Intervention group: Patients with standard treatment (head positioning, narcotic pain treatment, MOM for digestive function, heparin therapy, ulcer prophylaxis and normal saline serum

Sponsors

Qazvin University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patient age 18 to 60 years Patients with severe brain damage (GCS = 8) Patients who have not undergone surgery Informed consent of the first degree relatives of the patients and completion of the consent form

Exclusion criteria

Exclusion criteria: Chronic Kidney Disease End-Stage Renal Disease (ESRD) Pregnancy and breastfeeding Hemochromatosis patients Reluctance to cooperateIn the study Chronic liver diseases (cirrhosis, hepatitis, etc.) History of kidney stones Vitamin C allergy

Design outcomes

Primary

MeasureTime frame
Changes in the patient's clinical status and consciousness based on the GCS scale. Timepoint: At the time of entering the ICU, the second day, the fourth day and during transfer to the ward. Method of measurement: Glasgow Coma Scale.

Secondary

MeasureTime frame
The duration of the patient's stay in the ICU and the hospital. Timepoint: When discharged from the hospital. Method of measurement: Counting days of hospitalization.;8 and 28 day mortality rate. Timepoint: 8 and 28 days after ICU admission. Method of measurement: Counting days of hospitalization.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Valipour Jamnani

Qazvin University of Medical Sciences

mdrc46@yahoo.com+98 28 3333 6001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026