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The effect of regional analgesia with dexamethasone and dexmedetomidine

Comparison of the effect of regional analgesia with dexamethasone and dexmedetomidine on spinal surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230530058342N1
Enrollment
120
Registered
2023-10-05
Start date
2023-11-06
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain after discopathy surgery. Other acute postprocedural pain

Interventions

Intervention 1: Intervention group 1: For the dexamethasone group, 0.2 mg/kg of dexamethasone is placed inside the gelophane on the operation site before suturing the operation site. Each ampule of de

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 65 Years

Inclusion criteria

Inclusion criteria: All patients who are going to undergo posterior 1 or 2 lumbar spine surgery at ASA I-II level

Exclusion criteria

Exclusion criteria: History of oversensitivity to Dexamethasone History of oversensitivity to Dexmedetomidine History of severe Cardiac disease History of severe Pulmonary disease History or presence of arrhythmias Kidney failure Liver failure Pcychiatric disorder History of chronic pain Addiction to opioids History of longterm use of sedative medications

Design outcomes

Primary

MeasureTime frame
Pain level based on VAS 10 scale. Timepoint: Postoperative pain will be assessed every 30 minutes for the first 2 hours and then every 2 hours up to 24 hours using a 10 cm VAS. Method of measurement: VAS 10 Scale.

Secondary

MeasureTime frame
The time that the first pain killer is requested by the patient. Timepoint: As soon as the first painkiller is requested by the patient. Method of measurement: Based on the time that the first pain killer is requested by the patient.;The total amount of narcotics consumed by the patient in the first 24 hours after the operation. Timepoint: Every 30 minutes for the first 2 hours and then every 2 hours for 24 hours. Method of measurement: Based on the amount of narcotics consumed based on milligrams.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahshid Vaziri

Ahvaz University of Medical Sciences

vaziri-m@ajums.ac.ir+98 61 3374 3037

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026