The immediate effect of the novel spring-damper ankle-foot orthosis on margin of stability of affected and unaffected limbs during walking of patients diseased to MS

Evaluation of the immediate effect of the novel spring-damper ankle-foot orthosis on margin of stability of affected and unaffected limbs during walking of patients diseased to multiple sclerosis with drop foot

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230528058315N3

Enrollment

Registered

2025-08-12

Start date

2025-09-23

Completion date

Unknown

Last updated

2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis. Multiple sclerosis

Interventions

Intervention group: Each participant will be evaluated under two conditions: wearing shoes on both sides, and wearing a shoe on the unaffected side along with the new spring-damper orthosis on the aff

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Adults with unilateral foot drop caused by multiple sclerosis Ability to walk at least 25 steps without assistance Ability to complete at least 25 steps within a duration of 8 to 45 seconds Maximum grade of 3- (minus) in the manual muscle strength test for dorsiflexors and grade 3+ (plus) in knee extensor muscles Ability to walk without orthoses for up to ten meters Ability to achieve at least 5 degrees of passive dorsiflexion Completion of the Four Square Step Test (FSST) in less than 15 seconds

Exclusion criteria

Exclusion criteria: Having cardiovascular or respiratory problems Presence of limb impairment or amputation on the opposite side Concurrent use of other treatment methods (e.g., physiotherapy or surgery) during the study Having perceptual-cognitive impairments Presence of polyneuropathy Instability and imbalance while standing or walking Severe visual or hearing impairment History of spinal fracture or pain Participant's unwillingness to continue cooperation Absence of spasticity greater than grade 3 in the plantar flexor muscles (according to the Ashworth scale) scoring less than 5 on the disability scale

Design outcomes

Primary

Measure	Time frame
Margin of stability. Timepoint: After 5 minutes adaptation with orthosis. Method of measurement: Viacon motion analysis system and Kistler force plate.	—

Secondary

Measure	Time frame
Stride length. Timepoint: Immediately after receiving the orthosis. Method of measurement: Viacon Motion Analysis System.;Stride width. Timepoint: Immediately after receiving the orthosis. Method of measurement: Viacon Motion Analysis System.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEnsieh Pourhoseingholi

Hamedan University of Medical Sciences

ensihphd@gmail.com+98 81 3838 1571

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026