Improving sleep quality and cognitive functions and psychotherapy during sleep

Investigating the effect of time-locked auditory with electrical brain stimulation on the day sleep microstructures and cognitive functions through meaningful stimulus-targeted reactivation from memory

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230527058307N1

Enrollment

131

Registered

2023-06-15

Start date

2024-01-21

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Improving sleep quality and cognitive functions using simultaneous auditory and electrical stimulation, psychotherapy during sleep through meaningful auditory stimulation.

Interventions

Intervention 1: The first group: Electrical stimulation. Intervention 2: The second group: Neutral rhythmic sound stimulation simultaneously with Electrical stimulation. Intervention 3: The third grou

Eligibility

Sex/Gender

All

Age

20 Years to 30 Years

Inclusion criteria

Inclusion criteria: The average body mass index is 23/0 kg/m2 The average duration of normal sleep is 6-7 hours Obtaining a score of less than 6 in the PSQI questionnaire to evaluate the quality of sleep at night before the test session Having a regular sleep and wake rhythm (these two items are confirmed by using actigraphy or recording sleep and wake hours for 7 days before each intervention) lacking any known sleep disorders Not taking medicine during the test No smoking in the past year Avoiding any caffeinated beverages in the morning before the test sessions The normality of normal test results No history of psychiatric, endocrine, cardiac disorders Persian language

Exclusion criteria

Exclusion criteria: Diagnosed medical, psychiatric, and hearing disorders taking psychoactive drugs, narcotics or nicotine pregnant or lactating woman

Design outcomes

Primary

Measure	Time frame
K-complex, spindle waves and slow oscillations. Timepoint: Before and after interventions. Method of measurement: examination of waves changes with fast Fourier transform method.;Stanford sleepiness scale questionnaire. Timepoint: Before and after interventions. Method of measurement: Comparison of scores of questionnaire with statistical method of paired t-test.;Positive and Negative Affect Schedule (PANAS). Timepoint: Before and after interventions. Method of measurement: Comparison of scores of questionnaire with statistical method of paired t-test.;Pittsburgh Sleep Quality Index (PSQI). Timepoint: Before and after interventions. Method of measurement: Comparison of scores of questionnaire with statistical method of paired t-test.;Salivary cortisol. Timepoint: Before and after interventions. Method of measurement: changes in salivary cortisol level with statistical method of paired t-test.;Cognitive functions (declarative memory, control of general alertness and vigilance, and investigation of sustained attention and reaction time). Timepoint: Before and after interventions. Method of measurement: Comparison of individual performance in cognitive tasks(Paired Associate Learning(PAL), Psychomotor Vigilance Task (PVT)) with statistical method of paired t-test.	—

Measure

Time frame

K-complex, spindle waves and slow oscillations. Timepoint: Before and after interventions. Method of measurement: examination of waves changes with fast Fourier transform method.;Stanford sleepiness scale questionnaire. Timepoint: Before and after interventions. Method of measurement: Comparison of scores of questionnaire with statistical method of paired t-test.;Positive and Negative Affect Schedule (PANAS). Timepoint: Before and after interventions. Method of measurement: Comparison of scores of questionnaire with statistical method of paired t-test.;Pittsburgh Sleep Quality Index (PSQI). Timepoint: Before and after interventions. Method of measurement: Comparison of scores of questionnaire with statistical method of paired t-test.;Salivary cortisol. Timepoint: Before and after interventions. Method of measurement: changes in salivary cortisol level with statistical method of paired t-test.;Cognitive functions (declarative memory, control of general alertness and vigilance, and investigation of sustained attention and reaction time). Timepoint: Before and after interventions. Method of measurement: Comparison of individual performance in cognitive tasks(Paired Associate Learning(PAL), Psychomotor Vigilance Task (PVT)) with statistical method of paired t-test.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Reza Saebipour

Birjand University of Medical Sciences

saebipour@gmail.com+98 56 3162 6000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026