The effect of Pamidronate Injection in the Treatment of LCP Disease

Evaluation of the Effect of Monthly Intravenous Pamidronate in the Treatment of Legg Calve Perthes in Children

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230526058299N1

Enrollment

Registered

2023-07-01

Start date

2023-06-22

Completion date

Unknown

Last updated

2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Legg-Calve'-Perthes.

Interventions

Intervention 1: Intervention group: In addition to routine treatment, the group will receive pamidronate for 6 months. A 90 gram ampoule with a dose of 1 mg/kg will be injected every month. The drug w

Eligibility

Sex/Gender

All

Age

No minimum to 18 Years

Inclusion criteria

Inclusion criteria: Patients with LCPD Consent to participate in the study

Exclusion criteria

Exclusion criteria: Received previous treatments receiving other similar drugs

Design outcomes

Primary

Measure	Time frame
Disease Grade. Timepoint: Referral time, six months and one year after the intervention. Method of measurement: Imaging findings and physical examination.;Response to treatment. Timepoint: Referral time, six months and one year after the intervention. Method of measurement: Imaging findings and physical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNiloofar Shashaani

Shahid Beheshti University of Medical Sciences

shashaaniniloofar@gmail.com+98 21 2222 7021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026