bronchopulmonary dysplasia. Bronchopulmonary dysplasia originating in the perinatal period
Conditions
Interventions
Intervention 1: Intervention group: In the intervention group, in addition to surfactant, melatonin drops at a dose of 0.1 milligram per kilogram of the baby's weight will be administered as oral drop
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Days to 3 Days
Inclusion criteria
Inclusion criteria: Premature neonates between 26 and 32 weeks with respiratory distress syndrome need surfactant injection
Exclusion criteria
Exclusion criteria: Apgar five minutes less than four Evidence of necrotizing enterocolitis before surfactant administration chromosomal disorders, esophageal atresia, diaphragmatic hernia Evidence of congenital heart diseases other than Atrial Septal Defect and Patent ductus arteriosus Major congenital anomaly of heart failure requiring treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BRONCHOPULMONARY DYSPLASIA. Timepoint: Before initiation of the study, 28 and 56 days after birth. Method of measurement: Inspiratory oxygen fraction:The percentage of oxygen that is present in the air of the newborn, in order to investigate respiratory distress syndrome, the need for oxygen or respiratory assistance for more than 28 days after birth to investigate bronchopulmonary dysplasia. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactfatemeh serati
Shahid Beheshti University of Medical Sciences
Outcome results
None listed