glaucoma. Glaucoma
Conditions
Interventions
Intervention 1: Intervention group: The target group is subjected to a slow infusion with a microdrop of 0.5 µg/kg of the intravenous drug dexmedetomidine over fifteen minutes. Intervention 2: Control
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Those who complete the informed consent form Capable of communication Having intraocular pressure (IOP) above 25 mm Hg Those who are resistant to medical treatment and need glaucoma surgery Those with any type of glaucoma, including primary and secondary open-angle and angle-closure glaucoma
Exclusion criteria
Exclusion criteria: Allergy to drugs including the study drug before the intervention Patients with any corneal abnormalities Significant Cardiovascular disease(secondary and tertiary heart block) Congestive heart failure Chronic heart failure and uncontrolled blood pressure BMI above 35 Uncontrolled diabetes mellitus Chronic treatment with Clonidine Liver and renal failure Drug or alcohol abuse Coagulation disorders Pregnancy Patients with antipsychotic and antiepileptic therapy Mental disorders/dementia/deafness/difficulty communicating/inability to lie on back COPD INR above 1.7
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraocular pressure. Timepoint: immediately before the intervention and then five, ten, fifteen and twenty minutes after the intervention. Method of measurement: Tono-Pen AVIA tonometry device by ophthalmologist. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure. Timepoint: Simultaneously with the measurement of intraocular pressure. Method of measurement: Cardiac monitoring device.;Heart beat. Timepoint: Simultaneously with the measurement of intraocular pressure. Method of measurement: Cardiac monitoring device. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyedMostafa Alavirad
Mashhad University of Medical Sciences
Outcome results
None listed