Sepsis. Sepsis, unspecified organism
Conditions
Interventions
Intervention 1: Intervention group:Kidilact synbiotic supplement containing 10 strains of bacteria produced by zisttakhmir company with a dose of 2 sachets daily for 7 days. Intervention 2: Control gr
Sponsors
Vice President of Research and Technology, Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Months to 10 Years
Inclusion criteria
Inclusion criteria: Any Patient admitted to the Pediatric Intensive Care Unit with a Diagnosis of Sepsis and Possibility of Hospitalization for more than 4 Days in the PICU children aged 1 month to 10 years consent of parent to participation of their children to study
Exclusion criteria
Exclusion criteria: Immunodeficiency or Malignancy steroid Therapy or Immunotherapy Congenital Abnormalities Incompatible with life Previous Gastrointestinal Surgery in the last month Ulcerative Colitis Short Bowel Syndrome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Interleukin-6. Timepoint: The beginning of the study (before the start of the intervention) and the 7th day after the start of taking the synbiotic supplement. Method of measurement: Interleukin 6 ELISA kit. | — |
Secondary
| Measure | Time frame |
|---|---|
| C reactive protien. Timepoint: The beginning of the study (before the start of the intervention), 7 days after the start of taking the synbiotic supplement. Method of measurement: Measurement of serum levels.;Tumor necrosis factor. Timepoint: The beginning of the study (before the start of the intervention), 7 days after the start of taking the synbiotic supplement. Method of measurement: Measurement of serum levels.;Erythrocyte sedimentation rate. Timepoint: The beginning of the study (before the start of the intervention), 7 days after the start of taking the synbiotic supplement. Method of measurement: Measurement of serum levels. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Roudi
Mashhad University of Medical Sciences
Outcome results
None listed