Comparison of the effect of Low Level Laser Therapy and methylene blue-mediated Photodynamic Therapy with Laser in patient with oral ulcerative and erythematosus lichenoid reaction.

Comparison of the effect of Low Level Laser Therapy (660 nm) and Methylene Blue-mediated Photodynamic Therapy with laser (660 nm) in patient with oral ulcerative and erythematosus Lichenoid Reaction

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230522058261N1

Enrollment

Registered

2023-12-18

Start date

2023-12-19

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Erythematous and ulcerative Oral Lichenoid. Lichen planus

Interventions

Intervention 1: Intervention group: This group will include patients that laser 660 nm will be applied on the left side of their mouth. Intervention 2: Intervention group: On the right side of the sam

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Clinical diagnosis and pathology of oral Lichen Planus or Lichenoid drug eruption Erythematous and ulcerative types (erosive) Patient consent

Exclusion criteria

Exclusion criteria: Dysplasia changes in pathology report Lack of patient consent

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: Twice a week. Method of measurement: VAS.;Duration of pain relief erythematous and ulcerative lesions. Timepoint: Each treatment session and follow-up. Method of measurement: Based on the number of days.;Dimensional changes of the lesion. Timepoint: Twice a week. Method of measurement: Square millimeters.;Recovery time. Timepoint: Checking during treatment sessions and follow-up. Method of measurement: Number of days.	—

Measure

Time frame

Pain. Timepoint: Twice a week. Method of measurement: VAS.;Duration of pain relief erythematous and ulcerative lesions. Timepoint: Each treatment session and follow-up. Method of measurement: Based on the number of days.;Dimensional changes of the lesion. Timepoint: Twice a week. Method of measurement: Square millimeters.;Recovery time. Timepoint: Checking during treatment sessions and follow-up. Method of measurement: Number of days.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Mansour Shirani

Islamic Azad University

am_shirani@khuisf.ac.ir+98 31 3500 2153

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026