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The effect of ipratropium bromide spray on allergic rhinitis

Evaluation of the effect of ipratropium bromide spray on nasal hypersecretion (rhinorhea) in allergic rhinitis patients

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230522058254N1
Enrollment
140
Registered
2024-12-11
Start date
2024-12-21
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic Rhinitis.

Interventions

Intervention 1: Control group: The placebo (normal saline) along with budesonide (64 micro gram), 2 puffs per nostril, three times a day for two weeks, is administered. Intervention 2: Intervention gr

Sponsors

Eadeh Darou Teb Company
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1)All patients with a positive SPT (Skin Prick Test) reaction to mix 10 tree, mix 7 grass, mix 5 weed, and mix Dermatophagoides 2) No medication use for at least one month prior to the study. 3)No history of asthma or contact dermatitis in patients who did not benefit from previous medical treatments.

Exclusion criteria

Exclusion criteria: If the patient was diagnosed with seasonal allergic rhinitis (AR) or if AR was not classified as moderate to severe (i.e., it was a mild form of the disease). Use of medication or immunotherapy in the past month. Pregnancy or age 65 years. AR associated with allergic conditions affecting other organs, such as asthma or skin allergies. Patients with a history of prior turbinate surgery, nasal septal abnormalities, nasal polyps or tumors, nasal radiotherapy, or recurrent sinusitis.

Design outcomes

Primary

MeasureTime frame
Respiratory allergens. Timepoint: Start of the study. Method of measurement: Skin prick test.;Severity of rhinorrhea. Timepoint: At the start of the study and two weeks after the intervention. Method of measurement: The Visual Analogue Scale.;Drug side effects. Timepoint: Two weeks after the intervention. Method of measurement: Questioner.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Farhad Seif

Iranian academic center for education culture and research

farhad.seif@outlook.com+98 21 6646 2915

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026