Evaluation of the effect of quaternary HPV vaccine in the treatment of women with cervical intraepithelial neoplasia cin1 of Fatemiye Hospitan, Hamadan.
Conditions
Interventions
Intervention 1: Intervention group: Women in the intervention group will receive conservative treatment according to the ASCCP algorithm along with quadrivalent HPV vaccination (Gardasil). Gardasil ta
Sponsors
Hamedan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
21 Years to 45 Years
Inclusion criteria
Inclusion criteria: Age 21 to 45 years not currently pregnant not having had more than one sexual partner during their period received conservative treatment. women with histologically confirmed CIN 1
Exclusion criteria
Exclusion criteria: women who became pregnant received only one dose of the vaccine, or allergic to the vaccine Those who have been cin 1 for more than 24 month Those who do not participate in the study (non-cooperation) will be excluded from the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Histological biopsy status of CIN 1 lesions in two control and intervention groups. Timepoint: To measure this criterion, women are visited three times (months 12, 18,24) and undergo gynecological examination and pap smear test, colposcopy and annual biopsy and in 18 undergo gynecological examination and pap smear test (in case of pap smear test suspicious) have been placed. Method of measurement: To measure this criterion, women are visited three times (months 12, 18, 24) and undergo gynecological examination and pap smear test, colposcopy and annual biopsy and in 18 undergo gynecological examination and pap smear test (in case of pap smear test suspicious) have been placed. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMehrangiz Zamani bonab
Hamedan University of Medical Sciences
Outcome results
None listed