Enhancing knee Surgery Experience: Assessing the Impact of Intra-operative Virtual Reality Immersion on Anesthetic Consumption and Patient Satisfaction

Assessing the Impact of Intra-operative Virtual Reality Immersion on Anesthetic Consumption, Anxiety, Pain and Patient Satisfaction in Total Knee Arthroplasty Surgery: A Randomized Clinical Trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230522058251N4

Enrollment

Registered

2025-09-25

Start date

2025-09-06

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Total knee arthroplasty (right). Condition 2: Total knee arthroplasty (left).

Interventions

Intervention 1: Intervention group: Candidates for total knee arthroplasty, who are immersed in virtual reality during the procedure, and will receive fentanyl and midazolam at the discretion of the a

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Indication for unilateral total knee arthroplasty Informed consent to participate in the clinical trial Age between 18 to 65 years

Exclusion criteria

Exclusion criteria: Uncontrolled systemic diseases History of seizure History of migraine History of inner ear or middle ear dysfunction

Design outcomes

Primary

Measure	Time frame
The amount of anesthetic drug administered to the patient. Timepoint: After entering the operation room and during the surgical procedure. Method of measurement: The amount of Midazolam or Fentanyl injected to the patient as recorded in the surgery report note.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Hossein Mahrooz

Shahid Beheshti University of Medical Sciences

mohamad.mahrooz@gmail.com+98 912 130 8261

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026