Investigation of mixture of two blood coagulants effect on bleeding time after wisdom tooth surgery

Investigation of chitohem homogenous mixture powder and tranexamic acid ampoule effect on coagulation time and complications after the maxillary and mandibular third molar teeth extraction

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230521058248N1

Enrollment

Registered

2023-06-26

Start date

2023-07-23

Completion date

Unknown

Last updated

2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Maxillary and mandibular third molar extraction surgery. Inflammatory conditions of jaws

Interventions

Intervention 1: Intervention group: All patients undergo wisdom tooth extraction surgery by one person. The type of cut in all operations is similar and buccal flap type with distobuccal releasing, al

Eligibility

Sex/Gender

All

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Age between 18 and 35 years the third molar teeth of the mandible and maxilla embedded bilateral placed in class I, II, III, level A, B, and C based on the classification of Paul and Gray Gori require surgical tooth extraction.

Exclusion criteria

Exclusion criteria: Users of exogenous corticosteroidsthe the presence of systemic disorders respiratory and digestive diseases pregnant women and lactating mothers systemic fungal infections acute infections and active or silent tuberculosis

Design outcomes

Primary

Measure	Time frame
Duration of active bleeding. Timepoint: one, Two and three days after surgery on both intervention and control sides. Method of measurement: The way to measure pain is based on the vas scale and the amount of bleeding is based on the description of the patient.;Level of pain. Timepoint: The way to measure pain is based on the vas criterion and the amount of bleeding is based on the description of the patient. Method of measurement: The way to measure pain is based on the vas scale.	—

Measure

Time frame

Duration of active bleeding. Timepoint: one, Two and three days after surgery on both intervention and control sides. Method of measurement: The way to measure pain is based on the vas scale and the amount of bleeding is based on the description of the patient.;Level of pain. Timepoint: The way to measure pain is based on the vas criterion and the amount of bleeding is based on the description of the patient. Method of measurement: The way to measure pain is based on the vas scale.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactHasan Mesgari

Islamic Azad University

kmesgari@gmail.com+98 21 2256 4571

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026